Prospective evaluation of oral cannabis extracts in children with epilepsy

• Published in: Seizure (London, England) Vol. 72; pp. 23 - 27
• Main Authors: Knupp, Kelly G., Rice, John D., Helmkamp, Laura J., Galinkin, Jeffrey, Sempio, Cristina, Jost, Klawitter, Chapman, Kevin E.
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.11.2019
• Subjects: Cannabidiol; Cannabis; Epilepsy; Medical marijuana; THC; Cannabidiol; Cannabis; Medical marijuana; Epilepsy; THC

•Doses of OCE used are lower than used in randomized trials.•Response rates to OCE was 24%.•14% stopped OCE use due to increased seizures.•Levels of THC-COOH and CBD did not correlate with response. Interest in the use of artisanal cannabinoids in pediatric epilepsy has increased but safety and util...