The iron deficiency response in Arabidopsis thaliana requires the phosphorylated transcription factor URI

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 116; no. 50; pp. 24933 - 24942
• Main Authors: Kim, Sun A., LaCroix, Ian S., Gerber, Scott A., Guerinot, Mary Lou
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 10.12.2019
• Series: Inaugural Article
• Subjects: Arabidopsis - genetics; Arabidopsis - physiology; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Arabidopsis thaliana; Basic Helix-Loop-Helix Transcription Factors - genetics; Basic Helix-Loop-Helix Transcription Factors - metabolism; Biocompatibility; Biological Sciences; Chromatin; Free radicals; Helix-loop-helix proteins (basic); Homeostasis - genetics; Homeostasis - physiology; Hydroxyl radicals; Immunoprecipitation; INAUGURAL ARTICLE; Iron; Iron - deficiency; Iron - metabolism; Nutrient deficiency; Phosphorylation; Plants, Genetically Modified - genetics; Plants, Genetically Modified - physiology; Proteasomes; Proteins; Regulators; Signal transduction; Subgroups; Transcription factors; Ubiquitin-protein ligase; iron deficiency; iron homeostasis; Arabidopsis; bHLH transcription factor; phosphorylation

Iron is an essential nutrient for plants, but excess iron is toxic due to its catalytic role in the formation of hydroxyl radicals. Thus, iron uptake is highly regulated and induced only under iron deficiency. The mechanisms of iron uptake in roots are well characterized, but less is known about how...