Associations between Variants of the 8q24 Chromosome and Nine Smoking-Related Cancer Sites

• Published in: Cancer epidemiology, biomarkers & prevention Vol. 17; no. 11; pp. 3193 - 3202
• Main Authors: Park, Sungshim Lani, Chang, Shen-Chih, Cai, Lin, Cordon-Cardo, Carlos, Ding, Bao-Guo, Greenland, Sander, Hussain, Shehnaz K., Jiang, Qingwu, Liu, Simin, Lu, Ming-Lan, Mao, Jenny T., Morgenstern, Hal, Mu, Li-Na, Ng, Leslie J., Pantuck, Allan, Rao, Jianyu, Reuter, Victor E., Tashkin, Donald P., You, Nai-Chieh Y., Yu, Can-Qing, Yu, Shun-Zhang, Zhao, Jin-Kou, Belldegrun, Arie, Zhang, Zuo-Feng
• Format: Journal Article
• Language: English
• Published: United States American Association for Cancer Research 01.11.2008
• Subjects: 8q24 polymorphisms; Adolescent; Adult; Aged; Alleles; bladder; Case-Control Studies; Chi-Square Distribution; Chromosomes, Human, Pair 8 - genetics; esophagus; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; kidney; larynx; liver; Liver Neoplasms - ethnology; Liver Neoplasms - genetics; lung; Lung Neoplasms - ethnology; Lung Neoplasms - genetics; Male; Middle Aged; nasopharynx; neoplasms; Neoplasms - ethnology; Neoplasms - genetics; oropharynx; Otorhinolaryngologic Neoplasms - ethnology; Otorhinolaryngologic Neoplasms - genetics; Polymorphism, Single Nucleotide; Risk; Smoking - genetics; smoking-related cancers; SNP; stomach; Urinary Bladder Neoplasms - ethnology; Urinary Bladder Neoplasms - genetics

Recent genome-wide association studies identified key single nucleotide polymorphisms (SNPs) in the 8q24 region to be associated with prostate cancer. 8q24 SNPs have also been associated with colorectal cancer, suggesting that this region may not be specifically associated to just prostate cancer. T...