SIRT1 suppresses colorectal cancer metastasis by transcriptional repression of miR-15b-5p - Sun, Li-Na; Zhi, Zheng; Chen, Liang-Yan; Zhou, Qun; Li, Xiu-Ming; Gan, Wen-Juan; Chen, Shu; Yang, Meng; Liu, Yao; Shen, Tong; Xu, Yong; Li, Jian-Ming (Cancer letters, 2017)
Keywords: 3-Hydroxyacyl CoA Dehydrogenases - metabolism; Acetyl-CoA C-Acyltransferase - metabolism; Activator protein 1; Acyl-CoA oxidase; Animals; Apoptosis; Breast cancer; Caco-2 Cells; Cancer metastasis; Carbon-Carbon Double Bond Isomerases - metabolism; Cell Line, Tumor; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms - genetics; Colorectal Neoplasms - metabolism; Colorectal Neoplasms - pathology; Deacetylation; Enoyl-CoA Hydratase - metabolism; Experiments; Fatty-acid oxidation; Gene silencing; HCT116 Cells; Heterografts; HT29 Cells; Humans; Lung cancer; Metabolism; Metastases; Metastasis; Mice; Mice, Inbred BALB C; Mice, Nude; microRNA; MicroRNAs; MicroRNAs - genetics; MicroRNAs - metabolism; Neoplasm Metastasis; Oxidation; Proteins; Racemases and Epimerases - metabolism; Rodents; Signal Transduction; SIRT1; SIRT1 protein; Sirtuin 1 - genetics; Sirtuin 1 - metabolism; Transcription factors; Transcription, Genetic; Transfection; Tumors; Xenografts; China; Fatty-acid oxidation; microRNA; Cancer metastasis; SIRT1; Colorectal cancer