Biological Matrix Supply Chain Shortages: More Matrices Are Now Rare—the Case for Surrogate Matrices

• Published in: The AAPS journal Vol. 24; no. 2; p. 42
• Main Authors: Dubiel, Evan A., Myler, Heather, Arnold, Mark E., Bennett, Patrick, Gatz, Jeff, Groeber, Elizabeth, Gupta, Seema, Kane, Cheikh, Li, Fumin, Mylott, William, Noah, Courtney, O’Dell, Mark, Tewalt, Eric, Warrino, Dominic, Vick, Andrew
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 14.03.2022; Springer
• Subjects: Biochemistry; Biomedical and Life Sciences; Biomedicine; Biotechnology; COVID-19; Editorial; Epidemics; Health aspects; Humans; Logistics; Pandemics; Pharmacology/Toxicology; Pharmacy; Vaccines; pharmacokinetics; regulatory authorities; matrix; biomarkers; immunogenicity

The COVID-19 pandemic has strained the biological matrix supply chain. An upsurge in demand driven by numerous COVID-19 therapeutic and vaccine development programs to combat the pandemic, along with logistical challenges sourcing and transporting matrix, has led to increased lead times for multiple...