Fatigue in rheumatoid arthritis reflects pain, not disease activity

• Published in: Rheumatology (Oxford, England) Vol. 45; no. 7; pp. 885 - 889
• Main Authors: Pollard, L. C., Choy, E. H., Gonzalez, J., Khoshaba, B., Scott, D. L.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.07.2006; Oxford Publishing Limited (England)
• Subjects: Adult; Aged; Aged, 80 and over; Anti-TNF; Antirheumatic Agents - therapeutic use; Arthritis, Rheumatoid - complications; Arthritis, Rheumatoid - drug therapy; Biological and medical sciences; Clinical assessment; Cross-Sectional Studies; Depression - complications; Diseases of the osteoarticular system; DMARDs; Fatigue; Fatigue - etiology; Female; Humans; Inflammatory joint diseases; Male; Medical sciences; Middle Aged; Pain - complications; Pain Measurement; Rheumatoid arthritis; Severity of Illness Index; Tumor Necrosis Factor-alpha - antagonists & inhibitors; Immunopathology; Chronic; Pain; Rheumatoid arthritis; Diseases of the osteoarticular system; Rheumatology; Anti-TNF; Autoimmune disease; Fatigue; Inflammatory joint disease; DMARDs; Clinical assessment

Objective. We determined the amount of fatigue experienced by patients with RA, and its relationship to synovitis, pain and other common clinical features. We also examined to what extent RA fatigue is improved by disease-modifying antirheumatic drugs (DMARDs) and anti-tumour necrosis factor (TNF) t...