Anti-CD20 therapy depletes activated myelin-specific CD8⁺ T cells in multiple sclerosis - Sabatino, Joseph J.; Wilson, Michael R.; Calabresi, Peter A.; Hauser, Stephen L.; Schneck, Jonathan P.; Zamvil, Scott S. (Proceedings of the National Academy of Sciences - PNAS, 2019)
Keywords: Adolescent; Adult; Antibodies, Monoclonal - metabolism; Antigens, CD20 - immunology; Antigens, CD20 - metabolism; Biological Sciences; CD20 antigen; CD8 antigen; CD8-Positive T-Lymphocytes - cytology; CD8-Positive T-Lymphocytes - metabolism; Cells, Cultured; Epitopes; Female; Histocompatibility antigen HLA; Humans; Immunological memory; Immunotherapy; Influenza; Lymphocytes; Lymphocytes T; Major histocompatibility complex; Male; Memory cells; Middle Aged; Monoclonal antibodies; Multiple sclerosis; Multiple Sclerosis - immunology; Multiple Sclerosis - metabolism; Myelin; Myelin Proteins - metabolism; Pathogenesis; Peripheral blood; Phenotypes; Precursors; Therapy; Young Adult; CD8+ T cells; anti-CD20 therapy; multiple sclerosis; myelin antigen