Double-negative T cells remarkably promote neuroinflammation after ischemic stroke - Meng, Hailan; Zhao, Haoran; Cao, Xiang; Hao, Junwei; Zhang, He; Liu, Yi; Zhu, Min-sheng; Fan, Lizhen; Weng, Leihua; Qian, Lai; Wang, Xiaoying; Xu, Yun (Proceedings of the National Academy of Sciences - PNAS, 2019)
Keywords: Aged, 80 and over; Animals; Biological Sciences; Brain; Brain - immunology; Brain injury; Brain Ischemia - immunology; CD3 antigen; CD3 Complex - immunology; CD4 antigen; CD4 Antigens - immunology; CD8 antigen; CD8 Antigens - immunology; Central nervous system; Disease Models, Animal; FasL protein; Female; Head injuries; Homeostasis; Humans; Immunology; Inflammation; Inflammation - immunology; Ischemia; Lymphocytes; Lymphocytes T; Male; Mice; Mice, Inbred C57BL; Microglia - immunology; Peripheral blood; PTPN2 protein; Signal transduction; Stroke; Stroke - immunology; T-Lymphocyte Subsets - immunology; Time dependence; Tumor Necrosis Factor-alpha - metabolism; Tumor necrosis factor-α; DNTs; FasL; neuroinflammation; T cell-mediated immunity; ischemic stroke