Engineered Mesenchymal Stem Cells for Targeting Solid Tumors: Therapeutic Potential beyond Regenerative Therapy

• Published in: The Journal of pharmacology and experimental therapeutics Vol. 370; no. 2; pp. 231 - 241
• Main Authors: Cheng, Shen, Nethi, Susheel Kumar, Rathi, Sneha, Layek, Buddhadev, Prabha, Swayam
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2019; The American Society for Pharmacology and Experimental Therapeutics
• Subjects: Animals; Cell Engineering; Cell- and Tissue-Based Therapy - methods; Humans; Mesenchymal Stem Cells - cytology; Minireviews; Neoplasms - pathology; Neoplasms - therapy; Translational Research, Biomedical; LDGI; NP; IL; PLGA; MSC; DBCO

Mesenchymal stem cells (MSCs) have previously demonstrated considerable promise in regenerative medicine based on their ability to proliferate and differentiate into cells of different lineages. More recently, there has been a significant interest in using MSCs as cellular vehicles for targeted canc...