Cell-Based Versus Enzyme-Linked Immunosorbent Assay for the Detection of Acetylcholine Receptor Antibodies in Chinese Juvenile Myasthenia Gravis

• Published in: Pediatric neurology Vol. 98; pp. 74 - 79
• Main Authors: Yan, Chong, Li, Wenhui, Song, Jie, Feng, Xuelin, Xi, Jianying, Lu, Jiahong, Zhou, Shuizhen, Zhao, Chongbo
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2019
• Subjects: Acetylcholine receptor; cell-based assay; Diagnosis; ELISA; Juvenile myasthenia gravis; Juvenile myasthenia gravis; Diagnosis; cell-based assay; Acetylcholine receptor; ELISA

Patients in China with juvenile-onset myasthenia gravis present early, with a high prevalence of purely ocular symptoms, spontaneous remission rates, and low antibody seropositivity. Antibody detection using a cell-based assay has been reported to increase the diagnostic sensitivity in adult-onset m...