Rapid Determination of Tetracyclines in Drinking and Environmental Waters Using Fully Automatic Solid-Phase Extraction with Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry

• Published in: Molecules (Basel, Switzerland) Vol. 29; no. 12; p. 2921
• Main Authors: Zhang, Tongtong, Zhang, Xiangyang, Yu, Jiangmei, Hu, Hongmei, He, Pengfei, Li, Zhenhua, Fang, Yi, Li, Tiejun, Guo, Yuanming
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 19.06.2024; MDPI
• Subjects: Antibiotics; Aquaculture industry; automated solid-phase extraction; Automation; Chromatography; Chromatography, High Pressure Liquid - methods; Drinking water; Drinking Water - analysis; Drinking Water - chemistry; Ethylenediaminetetraacetic acid; isotope dilution; Limit of Detection; Mass spectrometry; Optimization; Oxytetracycline; Scientific imaging; Sea-water; Solid Phase Extraction - methods; Solvents; Tandem Mass Spectrometry - methods; tetracyclines; Tetracyclines - analysis; ultra-performance liquid chromatography–tandem mass spectrometry; Water; water matrix; Water Pollutants, Chemical - analysis; China; United States > US; automated solid-phase extraction; ultra-performance liquid chromatography–tandem mass spectrometry; isotope dilution; tetracyclines; water matrix

The abuse and irrational use of tetracyclines (TCs) in human medicine and animal husbandry has become a serious concern, affecting the ecological environment and human health. The aim of this study was to develop a sensitive and selective method using fully automatic solid-phase extraction coupled w...