Analysis of the responsible site for favipiravir resistance in RNA-dependent RNA polymerase of influenza virus A/PR/8/34 (H1N1) using site-directed mutagenesis - Komeno, Takashi; Furuta, Yousuke; Nakajima, Nozomi; Tani, Hideki; Morinaga, Yoshitomo (Antiviral Research, 2022)
Keywords: Amides; Antiviral Agents; Drug Resistance, Viral; Favipiravir; Humans; Influenza A Virus, H1N1 Subtype; Influenza virus; Influenza, Human; Mutagenesis, Site-Directed; Pyrazines; Replicon assay; RNA polymerase; RNA-Dependent RNA Polymerase; T-705; Virus Replication; Viruses; RNA polymerase; RLuc; RTP; DMEM; Influenza virus; FBS; RdRP; T-705; Favipiravir; EC50; vRNA; WT; Replicon assay