Acute exercise increases syndecan-1 and -4 serum concentrations

• Published in: Glycoconjugate journal Vol. 36; no. 2; pp. 113 - 125
• Main Authors: Lee, Sindre, Kolset, Svein O., Birkeland, Kåre I., Drevon, Christian A., Reine, Trine M.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2019; Springer Nature B.V
• Subjects: Adipose tissue; Adipose Tissue - metabolism; Adult; Biochemistry; Biomedical and Life Sciences; Blood flow; Exercise; Gene expression; Glycocalyx - metabolism; Humans; Insulin; Life Sciences; Male; Middle Aged; Muscle, Skeletal - metabolism; Musculoskeletal system; Original Article; Pathology; Physical activity; Physical fitness; Physical training; Serum levels; Skeletal muscle; Syndecan; Syndecan-1 - blood; Syndecan-1 - genetics; Syndecan-1 - metabolism; Syndecan-4 - blood; Syndecan-4 - genetics; Syndecan-4 - metabolism; Endothelial glycocalyx; Syndecans; Syndecan-shedding; Exercise; Insulin sensitivity; Dysglycemia

The effects of acute and long-term exercise on syndecans and the relationship to insulin sensitivity are not fully explored. We aimed to examine the effects of acute and 12 weeks of exercise on (1) serum levels of syndecan-1 and -4, (2) gene expression related to syndecan synthesis and modification...