Aging and cancer-related loss of insulin-like growth factor 2 imprinting in the mouse and human prostate
Loss of imprinting (LOI) is an epigenetic alteration involving loss of parental origin-specific expression at normally imprinted genes. A LOI for Igf2, a paracrine growth factor, is important in cancer progression. Epigenetic modifications may be altered by environmental factors. However, is not kno...
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Published in | Cancer research (Chicago, Ill.) Vol. 68; no. 16; pp. 6797 - 6802 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
15.08.2008
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Subjects | |
Online Access | Get full text |
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