Recent Trends in the Nucleophilic [18F]-radiolabeling Method with No-carrier-added [18F]fluoride

• Published in: Nuclear medicine and molecular imaging Vol. 44; no. 1; pp. 25 - 32
• Main Authors: Kim, Dong Wook, Jeong, Hwan-Jeong, Lim, Seok Tae, Sohn, Myung-Hee
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.04.2010; 대한핵의학회
• Subjects: Cardiology; Imaging; Medicine; Medicine & Public Health; Nuclear Medicine; Oncology; Orthopedics; Radiology; Review; Review Article; 방사선과학; Fluorinase; Tert alcohol; Fluorine-18; Iodonium salts; Nucleophilic fluorination; Ionic liquid

Noninvasive imaging in living subjects with positron emission tomography (PET) provides early detection of diseases in humans. For this application, it is necessary to prepare specific molecular imaging probes labeled with positron-emitting radioisotopes such as fluorine-18 for obtaining high-qualit...