Cholesterol-induced toxicity: An integrated view of the role of cholesterol in multiple diseases

• Published in: Cell metabolism Vol. 33; no. 10; pp. 1911 - 1925
• Main Authors: Song, Yongfeng, Liu, Junjun, Zhao, Ke, Gao, Ling, Zhao, Jiajun
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 05.10.2021
• Subjects: cell dysfunctions; cholesterol; cholesterol accumulation; cholesterol homeostasis; cholesterol toxicity; cell dysfunctions; cholesterol; cholesterol homeostasis; cholesterol toxicity; cholesterol accumulation

High levels of cholesterol are generally considered to be associated with atherosclerosis. In the past two decades, however, a number of studies have shown that excess cholesterol accumulation in various tissues and organs plays a critical role in the pathogenesis of multiple diseases. Here, we summ...