Timing of Chemotherapy After MammoSite Radiation Therapy System Breast Brachytherapy: Analysis of the American Society of Breast Surgeons MammoSite Breast Brachytherapy Registry Trial

• Published in: International journal of radiation oncology, biology, physics Vol. 72; no. 5; pp. 1441 - 1448
• Main Authors: Haffty, Bruce G., M.D, Vicini, Frank A., M.D, Beitsch, Peter, M.D, Quiet, Coral, M.D, Keleher, Angela, M.D, Garcia, Delia, M.D, Snider, Howard, M.D, Gittleman, Mark, M.D, Zannis, Victor, M.D, Kuerer, Henry, M.D, Whitacre, Eric, M.D, Whitworth, Pat, M.D, Fine, Richard, M.D, Keisch, Martin, M.D
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2008
• Subjects: Accelerated partial breast irradiation; Adult; Aged; Antineoplastic Agents - therapeutic use; BRACHYTHERAPY; Brachytherapy - methods; Brachytherapy - statistics & numerical data; Breast Neoplasms - drug therapy; Breast Neoplasms - pathology; Breast Neoplasms - radiotherapy; Breast Neoplasms - surgery; Breast-conserving surgery; CARCINOMAS; CHEMOTHERAPY; Combined Modality Therapy; Cosmesis; Female; Hematology, Oncology and Palliative Medicine; Humans; IRRADIATION; MAMMARY GLANDS; Mastectomy, Segmental - methods; Middle Aged; Neoplasm Staging; PATIENTS; Radiology; RADIOLOGY AND NUCLEAR MEDICINE; Reconstructive Surgical Procedures; Registries; Societies, Medical; SURGERY; Surgery, Plastic; Time Factors; Timing; Treatment Outcome; United States; United States; Accelerated partial breast irradiation; Cosmesis; Chemotherapy; Timing; Breast-conserving surgery

Purpose To evaluate cosmetic outcome and radiation recall in the American Society of Breast Surgeons registry trial, as a function of the interval between accelerated partial breast irradiation (APBI) and initiation of chemotherapy (CTX). Methods and Materials A total of 1440 patients at 97 institut...