An optimized fluorogenic ADAMTS13 assay with increased sensitivity for the investigation of patients with thrombotic thrombocytopenic purpura - Muia, J.; Gao, W.; Haberichter, S. L.; Dolatshahi, L.; Zhu, J.; Westfield, L. A.; Covill, S. C.; Friedman, K. D.; Sadler, J. E. (Journal of thrombosis and haemostasis, 2013)
Keywords: ADAM Proteins - analysis; ADAMTS13 Protein; Anticoagulants - chemistry; Case-Control Studies; Female; Fluorescent Dyes - chemistry; human; Humans; kinetics; Male; Mutation; Peptides - chemistry; Plasma; Plasmids - metabolism; Purpura, Thrombotic Thrombocytopenic - blood; Purpura, Thrombotic Thrombocytopenic - diagnosis; recombinant fusion proteins; Recombinant Fusion Proteins - metabolism; Reproducibility of Results; Sensitivity and Specificity; Substrate Specificity; Thrombocytopenia - blood; Thrombocytopenia - diagnosis; Thrombotic Microangiopathies - blood; Thrombotic Microangiopathies - diagnosis; thrombotic thrombocytopenic purpura; von Willebrand factor; von Willebrand Factor - chemistry; recombinant fusion proteins; ADAMTS13 protein; von Willebrand factor; substrate specificity; thrombotic thrombocytopenic purpura; kinetics; human