Novel microbiome signatures for non‐invasive diagnosis of adenoma recurrence after colonoscopic polypectomy

• Published in: Alimentary pharmacology & therapeutics Vol. 55; no. 7; pp. 847 - 855
• Main Authors: Liang, Jessie Qiaoyi, Zeng, Yao, Kwok, Grace, Cheung, Chun Pan, Suen, Bing Yee, Ching, Jessica Y. L., To, Ka Fai, Yu, Jun, Chan, Francis K. L., Ng, Siew Chien
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.04.2022; John Wiley and Sons Inc
• Subjects: Adenoma; Adenoma - diagnosis; Adenoma - genetics; Adenoma - surgery; Clostridiaceae; Colon; Colonoscopy; Colorectal cancer; Colorectal Neoplasms - diagnosis; Colorectal Neoplasms - genetics; Colorectal Neoplasms - surgery; Diagnosis; Feces; Humans; Microbiome Signature for Adenoma Recurrence; Microbiomes; Microbiota; Neoplasm Recurrence, Local - diagnosis; Neoplasm Recurrence, Local - genetics; Occult Blood; Original; Polymerase chain reaction; Polyps; Surveillance; Tumors

Summary Background We previously reported a panel of novel faecal microbiome gene markers for diagnosis of colorectal adenoma and cancer. Aim To evaluate whether these markers are useful in detecting adenoma recurrence after polypectomy. Methods Subjects were enrolled in a polyp surveillance study f...