Higher Concentration of Plasma Glial Fibrillary Acidic Protein in Wilson Disease Patients with Neurological Manifestations

• Published in: Movement disorders Vol. 36; no. 6; pp. 1446 - 1450
• Main Authors: Lin, Jie, Zheng, Yexiang, Liu, Ying, Lin, Yi, Wang, Qiqi, Lin, Xiao‐Hong, Zhu, Wenli, Lin, Wei‐Hong, Wang, Ning, Chen, Wan‐Jin, Fu, Ying
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.06.2021; Wiley Subscription Services, Inc
• Subjects: biomarker; Biomarkers; Brain injury; Brief Report; GFAP; Glial fibrillary acidic protein; Liver; Movement disorders; Neuronal-glial interactions; Plasma; Proteins; Regular Issue; Wilson disease; Wilson's disease; Wilson disease; biomarker; GFAP

ABSTRACT Background Wilson disease is a rare, disabling, neurological genetic disease. Biomarkers of brain damage are less well developed. Objective The aim of this study was to evaluate the utility of plasma glial fibrillary acidic protein as a biomarker for neurological involvement in patients wit...