Intra‐session and inter‐subject variability of 3D‐FID‐MRSI using single‐echo volumetric EPI navigators at 3T

• Published in: Magnetic resonance in medicine Vol. 83; no. 6; pp. 1920 - 1929
• Main Authors: Moser, Philipp, Eckstein, Korbinian, Hingerl, Lukas, Weber, Michael, Motyka, Stanislav, Strasser, Bernhard, Kouwe, Andre, Robinson, Simon, Trattnig, Siegfried, Bogner, Wolfgang
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.06.2020; John Wiley and Sons Inc
• Subjects: Brain - diagnostic imaging; Coefficient of variation; concentric rings; Cortex (motor); dynamic functional magnetic resonance spectroscopic imaging; Frequency drift; Glutamine; Head; Head movement; Humans; intra‐subject reproducibility; Metabolites; Navigators; Neuroimaging; Note—Spectroscopic Methodology; Phantoms, Imaging; real time motion correction; reliability; Reproducibility; Reproducibility of Results; Stability analysis; Stability augmentation; Temporal lobe; Three dimensional motion; Tracking; Variability; intra-subject reproducibility; real time motion correction; concentric rings; dynamic functional magnetic resonance spectroscopic imaging; reliability

Purpose In this study, we demonstrate the first combination of 3D FID proton MRSI and spatial encoding via concentric‐ring trajectories (CRTs) at 3T. FID‐MRSI has many benefits including high detection sensitivity, in particular for J‐coupled metabolites (e.g., glutamate/glutamine). This makes it hi...