Extension Study of PF‐05280586, a Potential Rituximab Biosimilar, Versus Rituximab in Subjects With Active Rheumatoid Arthritis

• Published in: Arthritis care & research (2010) Vol. 70; no. 11; pp. 1598 - 1606
• Main Authors: Cohen, Stanley B., Burgos‐Vargas, Rubén, Emery, Paul, Jin, Bo, Cronenberger, Carol, Vázquez‐Abad, María‐Dolores
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.11.2018; John Wiley and Sons Inc
• Subjects: CD19 antigen; Immunogenicity; Immunotherapy; Intravenous administration; Lymphocytes B; Monoclonal antibodies; Original; Pharmacodynamics; Pharmacokinetics; Remission; Rheumatoid Arthritis; Rituximab; Safety; United States > US
• ISSN: 2151-464X; 2151-4658; 2151-4658
• DOI: 10.1002/acr.23586

Objective This extension study provided continued treatment to subjects with active rheumatoid arthritis who had participated for ≥16 weeks in a pharmacokinetic similarity study of PF‐05280586 (potential rituximab biosimilar). Objectives were to evaluate overall pharmacokinetics, pharmacodynamics, i...