Central and extrapontine myelinolysis affecting the brain and spinal cord. An unusual presentation of pancreatic encephalopathy

• Published in: Frontiers in neurology Vol. 3; p. 135
• Main Authors: Hornik, Alejandro, Rodriguez Porcel, Federico J, Agha, Caroline, Flaster, Murray, Morales Vidal, Sarkis, Schneck, Michael J, Lee, John, Biller, José
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 2012; Frontiers Media S.A
• Subjects: extrapontine myelinolisis; leukoencephalopathy; Neuroscience; osmotic myelinolisis; pancreatic encephalopathy; pontine myelinolisis; leukoencephalopathy; osmotic myelinolysis; pontine myelinolysis; pancreatic encephalopathy; extrapontine myelinolysis
• ISSN: 1664-2295; 1664-2295
• DOI: 10.3389/fneur.2012.00135

Pancreatic encephalopathy refers to a gamut of neuropsychiatric symptoms complicating acute pancreatitis. Osmotic myelinolysis is a known complication of pancreatic encephalopathy. We evaluated a 58-year-old woman with pancreatic encephalopathy associated to pontine and extrapontine myelinolysis involving the brain and spinal cord. To our knowledge, this is the first clinic pathological case report of pancreatic encephalopathy involving the spinal cord.