Impairment of left atrial mechanics does not contribute to the reduction in stroke volume after active ascent to 4559 m

• Published in: Scandinavian journal of medicine & science in sports Vol. 29; no. 2; pp. 223 - 231
• Main Authors: Sareban, Mahdi, Perz, Tabea, Macholz, Franziska, Reich, Bernhard, Schmidt, Peter, Fried, Sebastian, Mairbäurl, Heimo, Berger, Marc M., Niebauer, Josef
• Format: Journal Article
• Language: English
• Published: Denmark Blackwell Publishing Ltd 01.02.2019; John Wiley and Sons Inc
• Subjects: Administration, Inhalation; Adult; Altitude; Atrial Function; Budesonide - administration & dosage; cardiac imaging; Echocardiography; Edema; Heart Atria - physiopathology; Heart Rate; high altitude pulmonary edema; Humans; hypoxia; Male; Mechanics; Middle Aged; Mountaineering; Original; Pulmonary arteries; Randomized Controlled Trials as Topic; speckle tracking echocardiography; Stroke Volume; Ventricular Dysfunction, Left; Ventricular Function, Left; hypoxia; high altitude pulmonary edema; cardiac imaging; speckle tracking echocardiography

Hypoxia challenges left ventricular (LV) function due to reduced energy supply. Conflicting results exist whether high‐altitude exposure impairs LV diastolic function and thus contributes to the high altitude‐induced increase in systolic pulmonary artery pressure (sPAP) and reduction in stroke volum...