Directed selection of influenza virus produces antigenic variants that match circulating human virus isolates and escape from vaccine‐mediated immune protection - DeDiego, Marta L.; Anderson, Christopher S.; Yang, Hongmei; Holden‐Wiltse, Jeanne; Fitzgerald, Theresa; Treanor, John. J.; Topham, David J. (Immunology, 2016)
Keywords: Amino acids; Animals; Antibodies, Viral - blood; antigenic drift; Antigenic Variation; Cell Line; Child, Preschool; circulating strains; Cohort Studies; Ferrets; haemagglutinin; Health risks; Hemagglutinin Glycoproteins, Influenza Virus - genetics; Hemagglutinin Glycoproteins, Influenza Virus - immunology; human influenza virus; Humans; Immunity, Humoral; Infant; Infections; Influenza; Influenza A Virus, H1N1 Subtype - immunology; Influenza A Virus, H3N2 Subtype - genetics; Influenza A Virus, H3N2 Subtype - immunology; Influenza Vaccines - immunology; influenza virus vaccination; Influenza, Human - immunology; influenza‐specific antibodies; Mutagenesis, Site-Directed; Mutation; Original; Prospective Studies; Seasons; Treatment Outcome; Vaccination; vaccine strain; Vaccines; Viruses; human influenza virus; haemagglutinin; influenza virus vaccination; influenza-specific antibodies; antigenic drift; circulating strains; vaccine strain