Retinal Thickness Predicts the Risk of Cognitive Decline in Parkinson Disease

• Published in: Annals of neurology Vol. 89; no. 1; pp. 165 - 176
• Main Authors: Murueta‐Goyena, Ane, Del Pino, Rocío, Galdós, Marta, Arana, Begoña, Acera, Marian, Carmona‐Abellán, Mar, Fernández‐Valle, Tamara, Tijero, Beatriz, Lucas‐Jiménez, Olaia, Ojeda, Natalia, Ibarretxe‐Bilbao, Naroa, Peña, Javier, Cortes, Jesus, Ayala, Unai, Barrenechea, Maitane, Gómez‐Esteban, Juan Carlos, Gabilondo, Iñigo
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.01.2021; Wiley Subscription Services, Inc
• Subjects: Adult; Atrophy; Biomarkers; Cognitive ability; Cognitive Dysfunction - complications; Cognitive Dysfunction - genetics; Confidence intervals; Dementia disorders; Evaluation; Female; Humans; Lewy bodies; Lewy Body Disease - genetics; Male; Middle Aged; Movement disorders; Mutation; Nerve Fibers - metabolism; Neurodegeneration; Neurodegenerative diseases; Optical Coherence Tomography; Parkinson Disease - complications; Parkinson Disease - congenital; Parkinson Disease - genetics; Parkinson's disease; Reduction; Retina; Retinal Ganglion Cells - metabolism; Risk; Thickness; Tomography; Tomography, Optical Coherence - methods; Visual Fields - genetics; Visual Fields - physiology

Objective This study was undertaken to analyze longitudinal changes of retinal thickness and their predictive value as biomarkers of disease progression in idiopathic Parkinson's disease (iPD). Methods Patients with Lewy body diseases were enrolled and prospectively evaluated at 3 years, includ...