Skeletal Structure in Postmenopausal Women With Osteopenia and Fractures Is Characterized by Abnormal Trabecular Plates and Cortical Thinning

• Published in: Journal of bone and mineral research Vol. 29; no. 5; pp. 1101 - 1109
• Main Authors: Stein, Emily M, Kepley, Anna, Walker, Marcella, Nickolas, Thomas L, Nishiyama, Kyle, Zhou, Bin, Liu, X Sherry, McMahon, Donald J, Zhang, Chiyuan, Boutroy, Stephanie, Cosman, Felicia, Nieves, Jeri, Guo, X Edward, Shane, Elizabeth
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.05.2014
• Subjects: Absorptiometry, Photon; Age Factors; Aged; Bone Density; Bone Diseases, Metabolic - diagnostic imaging; Bone Diseases, Metabolic - epidemiology; Bone Diseases, Metabolic - metabolism; BONE QUALITY; Female; FRACTURE; Fractures, Bone - diagnostic imaging; Fractures, Bone - epidemiology; Fractures, Bone - metabolism; Humans; MENOPAUSE; MICROARCHITECTURE; Middle Aged; OSTEOPOROSIS; Postmenopause - metabolism; Tomography, X-Ray Computed

ABSTRACT The majority of fragility fractures occur in women with osteopenia rather than osteoporosis as determined by dual‐energy X‐ray absorptiometry (DXA). However, it is difficult to identify which women with osteopenia are at greatest risk. We performed this study to determine whether osteopenic...