Effects and pregnancy outcomes of L‐carnitine supplementation in culture media for human embryo development from in vitro fertilization

• Published in: The journal of obstetrics and gynaecology research Vol. 44; no. 11; pp. 2059 - 2066
• Main Authors: Kim, Min Kyoung, Park, Jae Kyun, Paek, Soo Kyung, Kim, Ji Won, Kwak, In Pyung, Lee, Hee Jun, Lyu, Sang Woo, Lee, Woo Sik
• Format: Journal Article
• Language: English
• Published: Kyoto, Japan John Wiley & Sons Australia, Ltd 01.11.2018; Wiley Subscription Services, Inc
• Subjects: Adult; Animal models; Animals; antioxidant; Antioxidants; Antioxidants - pharmacology; ATP; Carnitine; Carnitine - pharmacology; Cell culture; Clinical outcomes; Culture Media; Dietary Supplements; embryo quality; Embryo, Mammalian; Embryonic Development - drug effects; Embryos; Female; Fertilization in Vitro; Humans; Implantation; In vitro fertilization; Infertility; L‐carnitine; Medical records; Mice; Mice, Inbred ICR; Pregnancy; Pregnancy Outcome; pregnancy rate; Reactive oxygen species; Retrospective Studies; Statistical analysis; Supplements; Trophectoderm; in vitro fertilization; embryo quality; antioxidant; L-carnitine; pregnancy rate

Aim Antioxidants have been studied to be effective in improving embryo qualities from in vitro fertilization. L‐carnitine (LC) has been known to reduce reactive oxygen species and enhance adenosine triphosphate production, which contribute to the development of a high‐quality embryo. This is the fir...