Positive selection drives adaptive diversification of the 4‐coumarate: CoA ligase (4CL) gene in angiosperms

• Published in: Ecology and evolution Vol. 5; no. 16; pp. 3413 - 3420
• Main Authors: Sun, Haiyan, Guo, Kai, Feng, Shengqiu, Zou, Weihua, Li, Ying, Fan, Chunfen, Peng, Liangcai
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.08.2015; John Wiley & Sons, Ltd
• Subjects: 4‐Coumarate: coenzyme A ligase; Abiotic factors; Amino acid sequence; Angiosperms; Biosynthesis; Catalysis; Coenzyme A; Divergence; diversification; Enzymes; Evolution; Flavonoids; Genes; Lignin; Metabolism; Metabolites; Original Research; Phylogenetics; Phylogeny; Positive selection; Proteins; Substrates; Terrestrial environments; United States > US; phylogeny; positive selection; 4-Coumarate: coenzyme A ligase; diversification; evolution

Lignin and flavonoids play a vital role in the adaption of plants to a terrestrial environment. 4‐Coumarate: coenzyme A ligase (4CL) is a key enzyme of general phenylpropanoid metabolism which provides the precursors for both lignin and flavonoids biosynthesis. However, very little is known about ho...