Family history of liver cancer may modify the association between HBV infection and liver cancer in a Chinese population

• Published in: Liver international Vol. 39; no. 8; pp. 1490 - 1503
• Main Authors: Liu, Xing, Baecker, Aileen, Wu, Ming, Zhou, Jin‐Yi, Yang, Jie, Han, Ren‐Qiang, Wang, Pei‐Hua, Jin, Zi‐Yi, Liu, Ai‐Min, Gu, Xiaoping, Zhang, Xiao‐Feng, Wang, Xu‐Shan, Su, Ming, Hu, Xu, Sun, Zheng, Li, Gang, Fu, Alan, Jung, Su Yon, Mu, Lina, He, Na, Li, Liming, Zhao, Jin‐Kou, Zhang, Zuo‐Feng
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.08.2019
• Subjects: Aged; Aged, 80 and over; Antigens; Bayesian analysis; Case-Control Studies; China - epidemiology; Confidence intervals; Deoxyribonucleic acid; DNA; family history; Family medical history; Female; Genetics; Health risk assessment; Hepatitis; Hepatitis B; Hepatitis B - complications; Hepatitis B e antigen; Hepatitis B surface antigen; hepatitis B Virus; hepatocellular carcinoma; Humans; Infections; interaction; Liver; Liver cancer; Liver Neoplasms - epidemiology; Liver Neoplasms - genetics; Liver Neoplasms - virology; Male; Markers; Middle Aged; Population studies; Risk factors; serological marker; China; interaction; hepatitis B Virus; serological marker; family history; hepatocellular carcinoma

Background & Aims The potential interaction between family history of liver cancer and HBV infection on liver cancer has not been fully examined. Methods We conducted a population‐based case‐control study composed of 2011 liver cancer cases and 7933 controls in Jiangsu province, China from 2003...