Fecal microbial DNA markers serve for screening colorectal neoplasm in asymptomatic subjects

• Published in: Journal of gastroenterology and hepatology Vol. 36; no. 4; pp. 1035 - 1043
• Main Authors: Liang, Jessie Qiaoyi, Wong, Sunny H, Szeto, Chun Ho, Chu, Eagle SH, Lau, Harry C, Chen, Yingxuan, Fang, Jingyuan, Yu, Jun, Sung, Joseph JY
• Format: Journal Article
• Language: English
• Published: Australia Wiley Subscription Services, Inc 01.04.2021; John Wiley and Sons Inc
• Subjects: Adenoma; Asymptomatic; Colorectal cancer; Colorectal carcinoma; Deoxyribonucleic acid; DNA; fecal immunochemical test (FIT); Feces; Gastroenterology; microbial makers; Neoplasia; Quantitation; Regular; screening; Tomography; Tumors; microbial makers; fecal immunochemical test (FIT); screening; colorectal cancer; neoplasia

Background and Aim We have previously shown that fecal microbial markers might be useful for non‐invasive diagnosis of colorectal cancer (CRC) and adenoma. Here, we assessed the application of microbial DNA markers, as compared with and in combination with fecal immunochemical test (FIT), in detecti...