Cathelicidin‐related antimicrobial peptide alleviates alcoholic liver disease through inhibiting inflammasome activation - Li, Fengyuan; Zhao, Cuiqing; Shao, Tuo; Liu, Yunhuan; Gu, Zelin; Jiang, Mengwei; Li, Huimin; Zhang, Lihua; Gillevet, Patrick M; Puri, Puneet; Deng, Zhong‐Bin; Chen, Shao‐Yu; et al. (The Journal of pathology, 2020)
Keywords: Alcohol use; ALD; Animals; Antimicrobial agents; Antimicrobial Cationic Peptides - genetics; Antimicrobial Cationic Peptides - metabolism; Antimicrobial peptides; Biomarkers - blood; Cell activation; CRAMP; Dysbacteriosis; Dysbiosis - genetics; Dysbiosis - metabolism; Dysbiosis - pathology; Hepatitis; Homeostasis; Humans; IL‐1β; Inflammasomes; Inflammasomes - genetics; Inflammasomes - metabolism; Interleukin-1beta - blood; Lipopolysaccharides; Liver - metabolism; Liver - pathology; Liver diseases; Liver Diseases, Alcoholic - genetics; Liver Diseases, Alcoholic - metabolism; Liver Diseases, Alcoholic - pathology; LPS; Macrophages; Male; Mice; Mice, Knockout; Oxidative Stress - genetics; Peptides; Serum levels; Uric acid; Uric Acid - blood; IL‐1β; ALD; CRAMP; uric acid; LPS