Transcriptional substrates underlying functional connectivity profiles of subregions within the human sensorimotor cortex

• Published in: Human brain mapping Vol. 43; no. 18; pp. 5562 - 5578
• Main Authors: Shen, Yuhao, Zhang, Cun, Cui, Shunshun, Wang, Rui, Cai, Huanhuan, Zhao, Wenming, Zhu, Jiajia, Yu, Yongqiang
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 15.12.2022
• Subjects: Allen human brain atlas; Brain; Brain Mapping - methods; Consortia; Data processing; Datasets; Dementia disorders; Developmental stages; Enrichment; functional connectivity; Gene expression; Genes; Heterogeneity; Homogeneity; Humans; Immune system; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Medical imaging; Mental disorders; Neural networks; Neuroimaging; resting‐state fMRI; Scanners; sensorimotor cortex; Sensorimotor Cortex - diagnostic imaging; Somatosensory cortex; Spatial analysis; subregion; Substrates; Transcriptomes; Transcriptomics; Allen human brain atlas; functional connectivity; sensorimotor cortex; resting-state fMRI; subregion; gene expression

The human sensorimotor cortex has multiple subregions showing functional commonalities and differences, likely attributable to their connectivity profiles. However, the molecular substrates underlying such connectivity profiles are unclear. Here, transcriptome‐neuroimaging spatial correlation analys...