Individual trabecula segmentation (ITS)–based morphological analysis of microscale images of human tibial trabecular bone at limited spatial resolution

• Published in: Journal of bone and mineral research Vol. 26; no. 9; pp. 2184 - 2193
• Main Authors: Liu, X Sherry, Shane, Elizabeth, McMahon, Donald J, Guo, X Edward
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.09.2011; Wiley; Oxford University Press
• Subjects: Aged; Aged, 80 and over; Biological and medical sciences; Elastic Modulus; Female; Fundamental and applied biological sciences. Psychology; HIGH‐RESOLUTION PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY; Humans; Image Processing, Computer-Assisted - methods; INDIVIDUAL TRABECULA SEGMENTATION; Male; MICRO–COMPUTED TOMOGRAPHY; Middle Aged; Skeleton and joints; Tibia - anatomy & histology; Tibia - diagnostic imaging; Tomography, X-Ray Computed - methods; TRABECULAR MICROARCHITECTURE; TRABECULAR TYPE; Vertebrates: osteoarticular system, musculoskeletal system; X-Ray Microtomography; Human; High resolution; TRABECULAR TYPE; Segmentation; MICRO-COMPUTED TOMOGRAPHY; Osteoarticular system; Vertebrata; Image analysis; TRABECULAR MICROARCHITECTURE; Mammalia; HIGH-RESOLUTION PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY; Tomography; Bone; INDIVIDUAL TRABECULA SEGMENTATION
• ISSN: 0884-0431; 1523-4681; 1523-4681
• DOI: 10.1002/jbmr.420

Individual trabecula segmentation (ITS), a rigorous model‐independent 3D morphological analysis, has been developed to assess trabecular plate and rod microstructure separately based on micro–computed tomographic (µCT) images. We examined the influence of the limited spatial resolution, noise, and a...