Can Helicobacter pylori serology still be applied as a surrogate marker to identify peptic ulcer disease in dyspepsia?

• Published in: Alimentary pharmacology & therapeutics Vol. 14; no. 5; pp. 615 - 624
• Main Authors: XIA, H. H.-X, KALANTAR, J. S, MITCHELL, H. M, TALLEY, N. J
• Format: Journal Article
• Language: English
• Published: Oxford UK Blackwell Publishing Ltd 01.05.2000; Blackwell
• Subjects: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal - adverse effects; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use; Biological and medical sciences; Biomarkers - analysis; Digestive system. Abdomen; Endoscopy; Enzyme-Linked Immunosorbent Assay - standards; Female; Functional investigation of the digestive system; Helicobacter Infections - complications; Helicobacter Infections - diagnosis; Helicobacter pylori - immunology; Humans; Investigative techniques, diagnostic techniques (general aspects); Male; Medical History Taking; Medical sciences; Middle Aged; Peptic Ulcer - diagnosis; Peptic Ulcer - microbiology; Predictive Value of Tests; Sensitivity and Specificity; Human; Spirillales; Dyspepsia; Spirillaceae; Biological marker; Serology; Enzyme immunoassay; Non steroidal antiinflammatory agent; Helicobacter pylori; Laboratory investigations; Digestive diseases; Bacteria; Diagnosis; ELISA assay; Anastomotic ulcer; Gastric disease

Background: Helicobacter pylori infection and associated peptic ulcer disease (PUD) has become less common in some countries. Aim: To determine if H. pylori serology alone or combined with a history of ingestion of non‐steroidal anti‐inflammatory drugs (NSAIDs) and an age threshold can be used as an...