Alopecia Universalis in a Patient with Common Variable Immunodeficiency
: A 12‐year‐old boy with common variable immunodeficiency (CVI) who developed severe alopecia is presented. His sister also had alopecia and recurrent infections and died of lung infection at the age of 7 years. The loss of hair in both children was total; the pathology of a scalp skin biopsy specim...
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| Published in | Pediatric dermatology Vol. 16; no. 4; pp. 305 - 307 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Boston, MA, USA
Blackwell Publishing Inc
01.07.1999
Blackwell |
| Subjects | |
| Online Access | Get full text |
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| Abstract | : A 12‐year‐old boy with common variable immunodeficiency (CVI) who developed severe alopecia is presented. His sister also had alopecia and recurrent infections and died of lung infection at the age of 7 years. The loss of hair in both children was total; the pathology of a scalp skin biopsy specimen was typical for alopecia areata. The boy was subjected to clinical and immunologic evaluation and the results were compatible with common variable immunodeficiency. |
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| AbstractList | A 12-year-old boy with common variable immunodeficiency (CVI) who developed severe alopecia is presented. His sister also had alopecia and recurrent infections and died of lung infection at the age of 7 years. The loss of hair in both children was total; the pathology of a scalp skin biopsy specimen was typical for alopecia areata. The boy was subjected to clinical and immunologic evaluation and the results were compatible with common variable immunodeficiency. : A 12‐year‐old boy with common variable immunodeficiency (CVI) who developed severe alopecia is presented. His sister also had alopecia and recurrent infections and died of lung infection at the age of 7 years. The loss of hair in both children was total; the pathology of a scalp skin biopsy specimen was typical for alopecia areata. The boy was subjected to clinical and immunologic evaluation and the results were compatible with common variable immunodeficiency. |
| Author | Kiliç, S. sebnem Sanal, Özden Ersoy, Fügen Tezcan, Ilhan Türkbay, Dursun |
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| References | 1997; 289 1980; 269 1986; 114 1984; 110 1989; 34 1976; 89 1991; 67 1989; 9 1996 1996; 1 1992 1994; 1 1996; 135 1981; 76 1996; 65 Ochs HD (e_1_2_4_2_2) 1996 e_1_2_4_5_2 Tunessen WW (e_1_2_4_6_2) 1994 e_1_2_4_8_2 e_1_2_4_7_2 e_1_2_4_9_2 Esterly NB (e_1_2_4_4_2) 1992 e_1_2_4_10_2 e_1_2_4_12_2 e_1_2_4_13_2 Lawton AR (e_1_2_4_3_2) 1996 e_1_2_4_14_2 e_1_2_4_15_2 Hordinsky‐Kramarczuk D (e_1_2_4_11_2) 1981; 76 e_1_2_4_16_2 |
| References_xml | – volume: 135 start-page: 204 year: 1996 end-page: 210 article-title: Ultrastructural abnormalities in the dermal papillae of both lesional and clinically normal follicles from alopecia areata scalps. publication-title: Br J Dermatol – volume: 89 start-page: 728 year: 1976 end-page: 731 article-title: Antibody deficiency and alopecia. publication-title: J Pediatr – volume: 1 year: 1994 – volume: 9 start-page: 22 year: 1989 end-page: 33 article-title: Clinical and immunologic analyses of 103 patients with common variable immunodeficiency. publication-title: J Clin Immunol – volume: 76 start-page: 326 year: 1981 article-title: Lymphocyte subset abnormalities in alopecia areata. publication-title: J Invest Dermatol – volume: 65 start-page: 167 year: 1996 end-page: 170 article-title: Congenital alopecia and nail dystrophy associated with severe functional T cell immunodeficiency in two sibs. publication-title: Am J Med Genet – year: 1996 – volume: 67 start-page: 291 year: 1991 end-page: 294 article-title: Alopecia totalis and vitiligo in common variable immunodeficiency. publication-title: Postgrad Med J – year: 1992 – volume: 269 start-page: 1 year: 1980 end-page: 11 article-title: Immunopathological studies on alopecia areata. publication-title: Arch Dermatol Res – volume: 289 start-page: 384 year: 1997 end-page: 388 article-title: Lesional alopecia areata T lymphocytes downregulate epithelial cell proliferation. publication-title: Arch Dermatol Res – volume: 114 start-page: 337 year: 1986 end-page: 347 article-title: Alopecia areata: alterations in the hair growth cycle and correlation with the follicular pathology. publication-title: Br J Dermatol – volume: 34 start-page: 55 year: 1989 end-page: 59 article-title: Associations of the skeletal and immune system. publication-title: Am J Med Genet – volume: 1 year: 1996 – volume: 110 start-page: 163 year: 1984 end-page: 170 article-title: Immunological profiles in alopecia areata. publication-title: Br J Dermatol – ident: e_1_2_4_14_2 doi: 10.1136/pgmj.67.785.291 – ident: e_1_2_4_15_2 doi: 10.1002/(SICI)1096-8628(19961016)65:2<167::AID-AJMG17>3.0.CO;2-O – ident: e_1_2_4_16_2 doi: 10.1002/ajmg.1320340111 – ident: e_1_2_4_5_2 doi: 10.1111/j.1365-2133.1986.tb02825.x – ident: e_1_2_4_8_2 doi: 10.1111/j.1365-2133.1984.tb07462.x – volume-title: Clinical immunology year: 1996 ident: e_1_2_4_3_2 contributor: fullname: Lawton AR – ident: e_1_2_4_13_2 doi: 10.1016/S0022-3476(76)80791-3 – ident: e_1_2_4_10_2 doi: 10.1007/BF00404452 – volume-title: Textbook of pediatrics year: 1992 ident: e_1_2_4_4_2 contributor: fullname: Esterly NB – volume: 76 start-page: 326 year: 1981 ident: e_1_2_4_11_2 article-title: Lymphocyte subset abnormalities in alopecia areata. publication-title: J Invest Dermatol contributor: fullname: Hordinsky‐Kramarczuk D – ident: e_1_2_4_7_2 doi: 10.1007/s004030050209 – volume-title: Immunologic disorders in infants and children year: 1996 ident: e_1_2_4_2_2 contributor: fullname: Ochs HD – volume-title: Principles and practice of pediatrics year: 1994 ident: e_1_2_4_6_2 contributor: fullname: Tunessen WW – ident: e_1_2_4_9_2 doi: 10.1111/j.1365-2133.1996.tb01148.x – ident: e_1_2_4_12_2 doi: 10.1007/BF00917124 |
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| Snippet | : A 12‐year‐old boy with common variable immunodeficiency (CVI) who developed severe alopecia is presented. His sister also had alopecia and recurrent... A 12-year-old boy with common variable immunodeficiency (CVI) who developed severe alopecia is presented. His sister also had alopecia and recurrent infections... A 12‐year‐old boy with common variable immunodeficiency (CVI) who developed severe alopecia is presented. His sister also had alopecia and recurrent infections... |
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| SubjectTerms | Alopecia Areata - etiology Alopecia Areata - immunology Biological and medical sciences Child Common Variable Immunodeficiency - complications Common Variable Immunodeficiency - therapy Consanguinity Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunoglobulins, Intravenous - therapeutic use Immunopathology Male Medical sciences |
| Title | Alopecia Universalis in a Patient with Common Variable Immunodeficiency |
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