Incapacity to control emotion in major depression may arise from disrupted white matter integrity and OFC‐amygdala inhibition - Zheng, Kai‐Zhong; Wang, Hua‐Ning; Liu, Jian; Xi, Yi‐Bin; Li, Liang; Zhang, Xi; Li, Jia‐Ming; Yin, Hong; Tan, Qing‐Rong; Lu, Hong‐Bing; Li, Bao‐Juan (CNS neuroscience & therapeutics, 2018)
Keywords: Adult; Amygdala; Amygdala - diagnostic imaging; Amygdala - drug effects; Amygdala - physiopathology; Antidepressive Agents - therapeutic use; Brain Mapping; Cortex (frontal); Depressive Disorder, Major - diagnostic imaging; Depressive Disorder, Major - drug therapy; dynamic causal modeling; effective connectivity; Emotions - drug effects; Emotions - physiology; Female; Frontal Lobe - diagnostic imaging; Frontal Lobe - drug effects; Frontal Lobe - physiopathology; Functional magnetic resonance imaging; Hemispheric laterality; Humans; Image Processing, Computer-Assisted; Limbic system; Magnetic Resonance Imaging; major depressive disorder; Male; Mental depression; Middle Aged; Myelination; Neural Pathways - diagnostic imaging; Neural Pathways - drug effects; Original; Patients; Psychiatric Status Rating Scales; Substantia alba; uncinate fasciculus; White Matter - diagnostic imaging; White Matter - drug effects; white matter integrity; uncinate fasciculus; white matter integrity; major depressive disorder; dynamic causal modeling; effective connectivity