Identification of circular RNAs in cardiac hypertrophy and cardiac fibrosis

• Published in: Frontiers in pharmacology Vol. 13; p. 940768
• Main Authors: Chen, Yan, Zhou, Junteng, Wei, Zisong, Cheng, Yue, Tian, Geer, Quan, Yue, Kong, Qihang, Wu, Wenchao, Liu, Xiaojing
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 08.08.2022
• Subjects: cardiac fibrosis; cardiac hypertrophy; ceRNA; circRNA; inflammation; Pharmacology

Cardiac hypertrophy initially serves as an adaptive response to physiological and pathological stimuli. Sustained hypertrophy progress to pathological cardiac hypertrophy, cardiac fibrosis and ultimately lead to heart failure, one of the leading medical causes of mortality worldwide. Intervention of...