Early-life residential exposure to soil components in rural areas and childhood respiratory health and allergy

• Published in: The Science of the total environment Vol. 466-467; pp. 338 - 344
• Main Authors: Devereux, Graham, Tagiyeva, Nara, Turner, Stephen W., Ayres, Jon G., Seaton, Anthony, Hudson, Gordon, Hough, Rupert L., Campbell, Colin D., Shand, Charles A.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2014
• Subjects: analysis; Asthma; Asthma - epidemiology; Asthma - etiology; chemistry; Child, Preschool; childhood; Children; Cohort Studies; Contamination; eczema; Environmental Exposure; Environmental Monitoring; epidemiology; etiology; Female; Humans; Hypersensitivity; Hypersensitivity - epidemiology; Hypersensitivity - etiology; Infant; inflammation; Longitudinal Studies; lung function; Male; Markvetenskap; microorganisms; nitric oxide; organic matter; particle size; parturition; Residential; residential areas; rural areas; Rural Health; Scotland; Scotland - epidemiology; Silt; Soil; Soil - chemistry; Soil Pollutants; Soil Pollutants - analysis; Soil Science; Scotland; FENO; NO; OR; SSD; Residential; CI; IQR; SIMD; GEEs; Contamination; Asthma; PEF; FVC; TIN; Soil; Silt; FEV1; Children; PM; General Estimating Equations; forced vital capacity; forced expiratory volume in 1s; Scottish Index of Multiple Deprivation; interquartile range; odds ratio; FE(NO); particulate matter; peak expiratory flow; triangulated irregular network; nitric oxide; Scottish Soils Database; fractional exhaled nitric oxide; FEV; confidence interval

The increase in asthma and allergies has been attributed to declining exposure to environmental microorganisms. The main source of these is soil, the composition of which varies geographically and which is a major component (40–45%) of household dust. Our hypothesis-generating study aimed to investi...