The change of plasma metabolic profile and gut microbiome dysbiosis in patients with rheumatoid arthritis

• Published in: Frontiers in microbiology Vol. 13; p. 931431
• Main Authors: Zhu, Jing, Wang, Tingting, Lin, Yifei, Xiong, Minghao, Chen, Jianghua, Jian, Congcong, Zhang, Jie, Xie, Huanhuan, Zeng, Fanwei, Huang, Qian, Su, Jiang, Zhao, Yi, Li, Shilin, Zeng, Fanxin
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 18.10.2022
• Subjects: gut bacterial; gut fungus; metabolic pathway; metabolomics; Microbiology; rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, which is associated with progressive disability, systemic complications, and early death. But its etiology and pathogenesis are not fully understood. We aimed to investigate the alterations in plasma metabolite profiles, gut bacteria...