An update on human and mouse glandular kallikreins
Human glandular kallikreins are secreted serine proteases, involved in many biological processes. Recently, the complete organization of the human and mouse genomic loci has been elucidated. These loci harbor the largest clusters of serine proteases within the human and mouse genomes. Mouse ortholog...
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| Published in | Clinical Biochemistry Vol. 37; no. 4; pp. 258 - 260 |
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| Main Authors | , , |
| Format | Book Review Journal Article |
| Language | English |
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Elsevier Inc
01.04.2004
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| Abstract | Human glandular kallikreins are secreted serine proteases, involved in many biological processes. Recently, the complete organization of the human and mouse genomic loci has been elucidated. These loci harbor the largest clusters of serine proteases within the human and mouse genomes. Mouse orthologs to all human kallikrein genes, except for
KLK2 and
KLK3 genes, have now been identified. Here, we describe an update of the genomic organization of these families in human and mouse, and provide some thoughts for future research directions. |
|---|---|
| AbstractList | Human glandular kallikreins are secreted serine proteases, involved in many biological processes. Recently, the complete organization of the human and mouse genomic loci has been elucidated. These loci harbor the largest clusters of serine proteases within the human and mouse genomes. Mouse orthologs to all human kallikrein genes, except for KLK2 and KLK3 genes, have now been identified. Here, we describe an update of the genomic organization of these families in human and mouse, and provide some thoughts for future research directions. Human glandular kallikreins are secreted serine proteases, involved in many biological processes. Recently, the complete organization of the human and mouse genomic loci has been elucidated. These loci harbor the largest clusters of serine proteases within the human and mouse genomes. Mouse orthologs to all human kallikrein genes, except for KLK2 and KLK3 genes, have now been identified. Here, we describe an update of the genomic organization of these families in human and mouse, and provide some thoughts for future research directions. |
| Author | Olsson, A.Yvonne Diamandis, Eleftherios P Yousef, George M |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/15003726$$D View this record in MEDLINE/PubMed https://lup.lub.lu.se/record/121516$$DView record from Swedish Publication Index |
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| Cites_doi | 10.1021/bi015775e 10.1515/BC.2002.113 10.1080/10408369891234219 10.1016/S1043-2760(98)00082-4 10.1515/BC.2001.002 10.1016/S0006-291X(02)02629-3 10.1021/bi002129r 10.1093/clinchem/48.8.1198 10.1093/clinchem/46.11.1855 10.1210/er.22.2.184 10.1016/S0090-4295(99)00585-3 10.1016/S0090-4295(97)00108-8 10.2174/1389202033350074 10.1016/B978-012249340-9/50007-3 10.1016/S0888-7543(05)80275-7 |
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Rev. doi: 10.1210/er.22.2.184 contributor: fullname: Yousef – volume: 55 start-page: 694 year: 2000 ident: 10.1016/j.clinbiochem.2003.12.013_BIB4 article-title: Clinical value of human glandular kallikrein 2 and free and total prostate-specific antigen in serum from a population of men with prostate-specific antigen levels 3.0 ng/mL or greater publication-title: Urology doi: 10.1016/S0090-4295(99)00585-3 contributor: fullname: Becker – ident: 10.1016/j.clinbiochem.2003.12.013_BIB3 doi: 10.1016/S0090-4295(97)00108-8 – volume: 4 start-page: 147 year: 2003 ident: 10.1016/j.clinbiochem.2003.12.013_BIB9 article-title: Human kallikreins: common structural features, sequence analysis and evolution publication-title: Current Genomics doi: 10.2174/1389202033350074 contributor: fullname: Yousef – ident: 10.1016/j.clinbiochem.2003.12.013_BIB5 doi: 10.1016/B978-012249340-9/50007-3 – volume: 14 start-page: 6 year: 1992 ident: 10.1016/j.clinbiochem.2003.12.013_BIB6 article-title: Characterization of the human kallikrein locus publication-title: Genomics doi: 10.1016/S0888-7543(05)80275-7 contributor: fullname: Riegman |
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| SubjectTerms | Animals Biochemistry and Molecular Biology Biokemi och molekylärbiologi Biologi Biological Sciences Genome Glandular kallikreins Human Humans Mice Mouse Natural Sciences Naturvetenskap Physical Chromosome Mapping Tissue Kallikreins - genetics |
| Title | An update on human and mouse glandular kallikreins |
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