An update on human and mouse glandular kallikreins

Human glandular kallikreins are secreted serine proteases, involved in many biological processes. Recently, the complete organization of the human and mouse genomic loci has been elucidated. These loci harbor the largest clusters of serine proteases within the human and mouse genomes. Mouse ortholog...

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Bibliographic Details
Published inClinical Biochemistry Vol. 37; no. 4; pp. 258 - 260
Main Authors Diamandis, Eleftherios P, Yousef, George M, Olsson, A.Yvonne
Format Book Review Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.04.2004
Subjects
Animals
Biochemistry and Molecular Biology
Biokemi och molekylärbiologi
Biologi
Biological Sciences
Genome
Glandular kallikreins
Human
Humans
Mice
Mouse
Natural Sciences
Naturvetenskap
Physical Chromosome Mapping
Tissue Kallikreins - genetics
Human
Mouse
Glandular kallikreins
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Summary:Human glandular kallikreins are secreted serine proteases, involved in many biological processes. Recently, the complete organization of the human and mouse genomic loci has been elucidated. These loci harbor the largest clusters of serine proteases within the human and mouse genomes. Mouse orthologs to all human kallikrein genes, except for KLK2 and KLK3 genes, have now been identified. Here, we describe an update of the genomic organization of these families in human and mouse, and provide some thoughts for future research directions.
Bibliography:ObjectType-Article-2
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ObjectType-Review-1
ISSN:0009-9120
1873-2933
1873-2933
DOI:10.1016/j.clinbiochem.2003.12.013