MHC II-PI3K/Akt/mTOR Signaling Pathway Regulates Intestinal Immune Response Induced by Soy Glycinin in Hybrid Grouper: Protective Effects of Sodium Butyrate

• Published in: Frontiers in immunology Vol. 11; p. 615980
• Main Authors: Yin, Bin, Liu, Hongyu, Tan, Beiping, Dong, Xiaohui, Chi, Shuyan, Yang, Qihui, Zhang, Shuang
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 18.01.2021
• Subjects: hybrid grouper (Epinephelus fuscoguttatus♀×E. lanceolatus♂); Immunology; intestinal inflammation; MHC II-PI3K/Akt/mTOR signaling pathway; sodium butyrate; soy glycinin

Soy glycinin (11S) is involved in immune regulation. As an additive, sodium butyrate (SB) can relieve inflammation caused by 11S. To further delve into the mechanisms. A diet containing 50% fishmeal was the control group (FM group), and the experimental groups consisted of the FM group baseline plus...