Hypoxia-Induced Pulmonary Blood Redistribution in Subjects With a History of High-Altitude Pulmonary Edema

• Published in: Circulation (New York, N.Y.) Vol. 101; no. 12; pp. 1418 - 1422
• Main Authors: Hanaoka, Masayuki, Tanaka, Masao, Ge, Ri-Li, Droma, Yunden, Ito, Atsuko, Miyahara, Takashige, Koizumi, Tomonobu, Fujimoto, Keisaku, Fujii, Tadashige, Kobayashi, Toshio, Kubo, Keishi
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 28.03.2000; American Heart Association, Inc
• Subjects: Altitude Sickness - complications; Biological and medical sciences; Blood Pressure - physiology; Echocardiography, Doppler; HLA Antigens - analysis; HLA-DR6 Antigen - analysis; Humans; Hypoxia - diagnostic imaging; Hypoxia - physiopathology; Lung - diagnostic imaging; Medical sciences; Pneumology; Pulmonary Circulation - physiology; Pulmonary Edema - diagnostic imaging; Pulmonary Edema - etiology; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases; Radionuclide Imaging; Stroke Volume; Radionuclide study; Sonography; Human; Lung disease; High altitude; Edema; Respiratory disease; Pathogenesis; Lung; Cardiovascular disease; Scintigraphy; Duplex ultrasonography; Pulmonary hypertension; Medical imagery; Hypoxia

Background —Pulmonary hypertension has been suggested to play an important role in development of high-altitude pulmonary edema (HAPE), and individual susceptibility has been suggested to be associated with enhanced pulmonary vascular response to hypoxia. We hypothesized that much greater pulmonary...