Characterisation of DOG-1 Expression in Salivary Gland Tumours and Comparison with Myoepithelial Markers

• Published in: Head & neck pathology (Totowa, N.J.) Vol. 13; no. 2; pp. 140 - 148
• Main Authors: Khurram, Syed A., Speight, Paul M.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.06.2019
• Subjects: Anoctamin-1 - biosynthesis; Biomarkers, Tumor - analysis; Dentistry; Humans; Medicine; Medicine & Public Health; Neoplasm Proteins - biosynthesis; Oral and Maxillofacial Surgery; Original Paper; Otorhinolaryngology; Pathology; Salivary Gland Neoplasms - diagnosis; Salivary Gland Neoplasms - metabolism; Myoepithelial; DOG-1; Acinic cell carcinoma; Secretory carcinoma; Salivary gland tumours; Luminal

DOG1 is an established diagnostic marker for gastrointestinal stromal tumours (GIST), but has been reported in salivary gland tumours (SGT) as an acinar and intercalated duct marker. However, its specificity and distribution is not well established. The aim of this study was to evaluate the diagnost...