Ferroptosis in inflammatory arthritis: A promising future

• Published in: Frontiers in immunology Vol. 13; p. 955069
• Main Authors: Chang, Siyuan, Tang, Mengshi, Zhang, Bikui, Xiang, Daxiong, Li, Fen
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 26.07.2022
• Subjects: cell death; ferroptosis; Immunology; inflammatory arthritis; iron accumulation; lipid peroxidation

Ferroptosis is a kind of regulatory cell death (RCD) caused by iron accumulation and lipid peroxidation, which is characterized by mitochondrial morphological changes and has a complex regulatory network. Ferroptosis has been gradually emphasized in the pathogenesis of inflammatory arthritis. In thi...