A carcinogenicity study of instant coffee in Swiss mice

• Published in: Food and chemical toxicology Vol. 28; no. 12; pp. 829 - 837
• Main Authors: Stalder, R., Bexter, A., Würzner, H.P., Luginbühl, H.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 1990; New York, NY Elsevier Science
• Subjects: Animals; Biological and medical sciences; Body Weight - drug effects; carcinogenesis; Carcinogenicity Tests; Coffee - toxicity; diet; Dose-Response Relationship, Drug; Eating - drug effects; Energy Intake - drug effects; Female; Food toxicology; instant coffee; Male; Medical sciences; Mice; Motor Activity - drug effects; Neoplasms - chemically induced; Organ Size - drug effects; Pregnancy; Random Allocation; Reproduction - drug effects; Sex Factors; Specific Pathogen-Free Organisms; Toxicology; Carcinogen; Vertebrata; Mammalia; Mouse; Carcinogenicity testing; Toxicity; Animal; Rodentia; Instant coffee

Commercially available regular instant coffee was given in the diet to barrier-maintained, specified pathogen-free Swiss mice for 2 yr. Groups of 150 males and 150 females were fed diets containing 10, 25 or 50 g instant coffee powder/kg. The animals had already been exposed to coffee in utero. Coff...