Meis2 Is Required for Inner Ear Formation and Proper Morphogenesis of the Cochlea

• Published in: Frontiers in cell and developmental biology Vol. 9; p. 679325
• Main Authors: Durán Alonso, María Beatriz, Vendrell, Victor, López-Hernández, Iris, Alonso, María Teresa, Martin, Donna M., Giráldez, Fernando, Carramolino, Laura, Giovinazzo, Giovanna, Vázquez, Enrique, Torres, Miguel, Schimmang, Thomas
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 28.05.2021
• Subjects: Cell and Developmental Biology; cochlea; inner ear; Meis; mouse; organ of corti

Meis genes have been shown to control essential processes during development of the central and peripheral nervous system. Here we have explored the roles of the Meis2 gene during vertebrate inner ear induction and the formation of the cochlea. Meis2 is expressed in several tissues required for inne...