Clinical Pharmacology of Platelet, Monocyte, and Vascular Cyclooxygenase Inhibition by Naproxen and Low-Dose Aspirin in Healthy Subjects - Capone, Marta L.; Tacconelli, Stefania; Sciulli, Maria G.; Grana, Marilena; Ricciotti, Emanuela; Minuz, Pietro; Di Gregorio, Patrizia; Merciaro, Gabriele; Patrono, Carlo; Patrignani, Paola (Circulation (New York, N.Y.), 2004)
Keywords: 6-Ketoprostaglandin F1 alpha - analogs & derivatives; 6-Ketoprostaglandin F1 alpha - urine; Adult; Aspirin - administration & dosage; Aspirin - pharmacology; Biological and medical sciences; Blood and lymphatic vessels; Blood Platelets - drug effects; Blood Platelets - enzymology; Cardiology. Vascular system; Cardiotonic Agents - pharmacology; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors - pharmacology; Dinoprostone - blood; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Endothelial Cells - drug effects; Endothelial Cells - enzymology; Endothelium, Vascular - cytology; Endothelium, Vascular - drug effects; Endothelium, Vascular - enzymology; Female; Humans; Isoenzymes - antagonists & inhibitors; Isoenzymes - blood; Male; Medical sciences; Membrane Proteins; Middle Aged; Monocytes - drug effects; Monocytes - enzymology; Naproxen - pharmacology; Prostaglandin-Endoperoxide Synthases - blood; Prostaglandins I - biosynthesis; Thromboxane B2 - analogs & derivatives; Thromboxane B2 - blood; Thromboxane B2 - urine; Human; Prostaglandin-endoperoxide synthase; Monocyte; Enzyme; Arachidonic acid derivatives; Low dose; Cardiovascular disease; Acetylsalicylic acid; Epoprostenol; Platelet; Eicosanoid; Naproxen; Clinical pharmacology; Oxidoreductases; Thromboxane