Sleep, a Governor of Morbidity in PTSD: A Systematic Review of Biological Markers in PTSD-Related Sleep Disturbances

• Published in: Nature and science of sleep Vol. 12; pp. 545 - 562
• Main Authors: Maguire, Daniel G, Ruddock, Mark W, Milanak, Melissa E, Moore, Tara, Cobice, Diego, Armour, Cherie
• Format: Journal Article
• Language: English
• Published: New Zealand Taylor & Francis Ltd 01.01.2020; Dove
• Subjects: Adrenal glands; Brain-derived neurotrophic factor; Chronic fatigue syndrome; Endorsements; Growth factors; Hormones; Hypotheses; Inflammation; Insomnia; Mental disorders; Military deployment; Morbidity; Physiology; Population; Post traumatic stress disorder; Review; Sleep; Systematic review; Trauma; sleep disturbances; post-traumatic stress disorder; nightmares; biomarkers; insomnia

Sleep disturbances (SD) are the most impactful and commonly reported symptoms in post-traumatic stress disorder (PTSD). Yet, they are often resistant to primary PTSD therapies. Research has identified two distinct SDs highly prevalent in PTSD; insomnia and nightmares. Those who report SDs prior to a...